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Bioprocess Chromatography Media Market Trends and Forecast

The future of the global bioprocess chromatography media market looks promising with opportunities in the biopharmaceutical and laboratory research markets. The global bioprocess chromatography media market is expected to grow with a CAGR of 5.1% from 2025 to 2031. The major drivers for this market are the rising demand for biologics & biosimilars, the growing focus on personalized medicine, and the increasing adoption of advanced bioprocessing technologies.

• Lucintel forecasts that, within the type category, ion exchange is expected to witness the highest growth over the forecast period.
• Within the application category, biopharmaceutical is expected to witness higher growth.
• In terms of region, North America is expected to witness the highest growth over the forecast period.
Gain valuable insights for your business decisions with our comprehensive 150+ page report. Sample figures with some insights are shown below.

Bioprocess Chromatography Media Market Trends and Forecast

Bioprocess Chromatography Media Market by Segment

Emerging Trends in the Bioprocess Chromatography Media Market

The bioprocess chromatography media industry is being influenced by a number of dominant emerging trends that represent the biopharmaceutical industry ongoing quest for more efficiency, cost savings, and improved product quality. These trends are affecting the development, use, and strategic placement of chromatography media, encouraging innovation and adjustment in the entire bioprocessing process. With biologics growing more complicated and manufacturing requirements escalating, these trends are essential in defining the future of bioseparation.
• Move Toward Continuous Chromatography: One key emerging trend is the speeding up move toward continuous chromatography processes. In contrast to traditional batch strategies, continuous chromatography allows for unperturbed purification, resulting in increased productivity, reduced equipment footprints, and lower buffer use. This trend fuels the creation of media best suited for continuous use, with features such as fast cycling, high flow rates, and durable performance under long-term use, greatly improving manufacturing efficiency.
• High-Capacity and High-Resolution Media Development: The industry is seeing a robust trend towards the creation of new chromatography media with higher binding capacity and increased resolution. With growing biopharmaceutical titers and more complex product impurity profiles, there is a need for media that can support higher loads with excellent separation efficiency. The trend here is centered on innovative ligand chemistries and bead engineering to deliver best-in-class purification performance.
• Single-Use Chromatography Systems and Pre-Packed Columns Adoption: A growing trend is the growing use of single-use chromatography systems and pre-packed columns. These single-use options avoid cleaning validation, lower the possibility of cross-contamination, and provide increased flexibility as well as quicker turnaround times. This trend is a result of the need to decrease operational costs, enhance process safety, and simplify manufacturing, especially in the case of clinical trials and multi-product plants.
• Downstream Processing Integration of Automation and Digitalization: The industry is witnessing a trend of integrating automation and digitalization into downstream processing, such as chromatography steps. This entails cutting-edge control systems, real-time monitoring, and data analysis for process optimization, predictive maintenance, and quality assurance. This trend will enhance process robustness, minimize human error, and facilitate intelligent decision making, resulting in more efficient and reliable biopharmaceutical purification.
• Growing Need for Specialty Media for New Biologics: There is a growing demand trend for very specialized chromatography media designed for new biologics, including cell and gene therapies, exosomes, and viral vectors. These intricate molecules sometimes need customized separation approaches because of their size, delicacy, and personal impurity profiles. This demand spurs research and development of bespoke media solutions to tackle the purification challenge presented by these new therapeutic modalities.
These nascent trends are deeply transforming the bioprocess chromatography media market by compelling it towards higher efficiency, flexibility, and specialization. The market is changing with an incredible emphasis on continuous processing, high-performance media, and single-use technology to serve the growing needs of the biopharmaceutical industry. This change is driving innovation in media design and use at a faster pace, ultimately facilitating quicker, lower-cost, and higher-quality production of life-saving biologics.
Emerging Trends in the Bioprocess Chromatography Media Market

Recent Development in the Bioprocess Chromatography Media Market

The bioprocess chromatography media industry has witnessed a number of landmark recent innovations, spurred by the growing worldwide need for sophisticated purification technologies for the biopharmaceutical sector. With the pipeline of biologics, such as monoclonal antibodies, vaccines, and cell and gene therapies, growing, cost-effective and efficient separation technologies take precedence. Such innovations are aimed at optimizing media performance, throughput, and product quality consistency, mirroring the trend towards more intensified and continuous bioprocessing practices in the sector.
• Resin Chemistry Advances to Increased Binding Capacity: One of the key developments in recent times is the progress in resin chemistry, with the development of chromatography media with greater binding capacities. This enables an increase in target molecules bound per unit volume of media, resulting in greatly enhanced throughput and decreased column size and expense. This is important for dealing with the increasing titers from upstream bioprocesses and improving the overall productivity of downstream purification.
• Greater Use of Continuous Chromatography Systems: Recent trends indicate increased uptake of continuous chromatography systems, such as multi-column and simulated moving bed (SMB) technologies. This move away from batch processing conserves resources for buffers, reduces equipment footprint, and improves process economics. This trend is prompting the demand for media specifically engineered for rapid cycling and rugged operation under continuous flow.
• Growth in Single-Use and Pre-Packed Column Solutions: The industry has seen substantial growth in the development of single-use and pre-packed chromatography column products. These pre-formulated solutions cut preparation time, reduce cleaning and validation procedures, and lower cross-contamination risk. This growth addresses the increasing demand for flexible, effective, and safer processes of manufacturing, especially for multi-product plants and clinical-scale manufacture.
• Media Development for New Biologics and Innovative Therapies: One of the most important developments is the targeted research and development of proprietary chromatography media specifically for next-generation biologics, including viral vectors for gene therapy, exosomes, and cell therapy products. These sensitive and complex biomolecules need highly specific and mild purification technologies. This innovation overcomes the distinctive challenges involved in the purification of these next-generation therapeutic modalities, allowing their large-scale production.
• Integration of Automation and Process Analytical Technology: Current advances involve the growing incorporation of automation and Process Analytical Technology (PAT) into chromatography systems. This enables real-time monitoring, feedback control, and automated optimization of purification steps. This advance improves process understanding, validates consistent product quality, minimizes manual intervention, and ultimately results in more robust and efficient biopharmaceutical production.
These new advancements are significantly influencing the market for bioprocess chromatography media by catalyzing a paradigm shift to more efficient, cost-saving, and flexible purification solutions. The market is defined by product innovations that maximize media performance, simplify processes, and meet the unique demands of disparate biopharmaceutical products. This transformation is essential to drive drug development faster, lower manufacturing costs, and eventually make life-saving biologics available at affordable prices to patients worldwide.

Strategic Growth Opportunities in the Bioprocess Chromatography Media Market

The bioprocess chromatography media industry offers a number of strategic opportunities for growth across primary applications, fueled by the growing biopharmaceutical sector and the accelerating need for high-purity biologics. With its role as a crucial element of downstream processing, understanding and taking advantage of these application-specific areas is paramount to industry players. Utilizing the next wave of media technology advances and responding to changing industry requirements will be instrumental in realizing sustainable growth and sustaining competitiveness in this critical segment.
• Monoclonal Antibodies (abs) Purification: High Throughput and Cost Reduction: Monoclonal antibody (maybe) purification presents a major strategic growth opportunity. abs continue as the largest biologics market segment, and a constant pressure exists to decrease their cost of manufacture but still ensure high purity. Opportunities exist in creating high capacity, high performance, and economical chromatography media tailored for maybe purification, such as protein A surrogates and high performance polishing resins, to deliver greater throughput and process intensification.
• Vaccine Production: Scalability and Speed: The vaccine production industry offers a strong growth opportunity, especially against the backdrop of worldwide health emergencies. Vaccines demand efficient and scalable purification techniques. Strategic expansion includes creating chromatography media that facilitate fast purification, high productivity, and stable performance for a wide range of vaccine formats, including viral vectors and recombinant proteins. This satisfies the urgent requirement for short turnaround times and large volumes.
• Cell and Gene Therapy Purification: Gentle and Specialised Media: The emerging market of cell and gene therapies (CGTs) presents a special and high-growth prospect. CGTs are complex and sometimes delicate biological entities that must be purified by highly specialized and gentle procedures. Room exists to create new chromatography media with low shear forces and high specificity for viral vectors, plasmids, and cell constituents that maintain product integrity and viability while reaching necessary levels of purity.
• Biosimilar and Bio-better Manufacturing: Cost-Effective and Efficient Options: Manufacturing biosimilars and bio-betters is a robust strategic growth opportunity. These drugs seek to provide cost-effective substitutes or upgraded versions of current biologics, requiring economical and efficient purification methods. Strategic growth is to supply chromatography media that deliver high performance at a competitive cost, allowing manufacturers to minimize overall cost of production for biosimilars and bio-betters without compromising on quality.
• Platform Development of Continuous Bioprocessing: Integrated Solutions: Shifting toward continuous bioprocessing is a major strategic possibility. It entails the creation of chromatography media and integrated solutions that integrate well into continuous purification processes. Possibilities exist in the design of media with quick kinetics, high stability, and reusability for multi-column operation, together with developing real-time monitoring and control systems to support end-to-end continuous manufacture of biologics.
These strategic opportunities for growth are having a profound effect on the bioprocess chromatography media market by driving specialization, innovation, and efficiency in major applications. The industry is changing to address the unique purification needs of varied biologics, from high-volume abs to sensitive cell and gene therapies. This application-driven strategy is driving substantial growth in research and development, compelling customized media solutions, and ultimately broadening the marketÄX%$%Xs scope and its important contribution to the development of biopharmaceutical production.

Bioprocess Chromatography Media Market Driver and Challenges

The bioprocess chromatography media market is affected by a multifaceted interaction of significant drivers and challenges, which include a range of technological, economic, and regulatory forces. These factors as a whole determine market demand, shape product innovation, and decide market accessibility. Deep understanding of these forces and probable deterrents is essential for market players to efficiently move in the direction, harness emerging prospects, and cover risks, and hence ensure sustainable growth and competitive advantage in a transforming industrial landscape.
The factors responsible for driving the bioprocess chromatography media market include:
1. Expanding Biopharmaceutical Sector and Biologics Pipeline: A key growth driver is the strong expansion of the worldwide biopharmaceutical market, specifically the increasing pipeline of biologics including monoclonal antibodies, recombinant proteins, vaccines, and cell and gene therapies. With more complicated and effective biotherapeutics coming through clinical trials and entering commercial production, the need for high-purity and high-efficiency separation technologies such as chromatography media increases, driving market growth.
2. Growing Emphasis on Downstream Processing Cost Saving and Efficiency: The ongoing pressure on biopharmaceutical manufacturers to enhance downstream processing efficiency and lower overall cost of production is a major driver. Chromatography media form the foundation of purification, and developments that provide greater binding capacity, increased flow rates, and extended lifetimes consequently lead directly to cost savings as well as higher throughput, and thus are extremely attractive for improving manufacturing economics.
3. Technological Advances in Chromatography Media: Continued technological improvements in chromatography media design, such as new ligand chemistries, better matrix materials, and better bead morphology, are central drivers. They result in media with greater selectivity, increased resolution, and greater ruggedness to perform more difficult separations and satisfy demanding purity needs in a wide range of complex and diverse biomolecules.
4. Increased Demand for Biosimilars and Bio-betters: The growing worldwide demand for biosimilars and bio-betters is a major driving force. The products seek to offer lower-cost or better alternatives for current biologics, and thus require cost-effective and efficient manufacturing processes. High-performance chromatography media play a key role in maintaining biosimilarsÄX%$%X quality, purity, and comparability to their reference products, thus facilitating their market launch and uptake.
5. Shift Towards Continuous Bioprocessing: The bioprocessing industry move towards continuous operation, which benefits the manufacturing process through a smaller footprint of equipment, lower operational expenditure, and higher productivity, is one of the key drivers. This movement promotes the creation of chromatography media for continuous operation, as well as for multi-column systems to allow trouble-free integration with intensified upstream and downstream processes.
Challenges in the bioprocess chromatography media market are:
1. High Cost of Advanced Chromatography Media: One of the major challenges for the bioprocess chromatography media industry is the high price of using advanced, high-performance media. Although such media have superior advantages in terms of purity and efficiency, their upfront cost can be very expensive, especially for small biotechnology firms or those in developing economies. This might restrict general adoption even though there are ultimate advantages.
2. Technical Expertise and Training Needs: Operation and bioprocess chromatography system optimization, particularly with new media, demand considerable technical competence and expert training. Method complexity, scale-up, and troubleshooting can present a challenge, especially in an area with a less sophisticated biopharmaceutical staff. This shortage of trained personnel can slow down efficient implementation and application of new media.
3. Alternative Purification Technologies Competition: The bioprocess chromatography media industry is challenged by competing purification technologies like membrane chromatography, precipitation, and crystallization. Although chromatography is still the gold standard in most applications, ongoing innovation in these alternative technologies, which potentially have certain benefits in cost, speed, or scalability for a particular molecule, can influence the growth and share of traditional media.
The interaction of these drivers and challenges provides a dynamic and multifaceted environment for the bioprocess chromatography media market. Although the rapidly increasing demand from the biopharmaceutical sector, ongoing technological innovations, and the drive for efficiency are strong drivers, the high expense, the requirement for expert skills, and competition from other technologies are strong impediments. The future of the market will rest on the industryÄX%$%Xs capacity to innovate to reduce costs, close skills gaps, and continue to show the superior performance and flexibility of chromatography media to prove it remains pivotal in biopharmaceutical production.

List of Bioprocess Chromatography Media Companies

Companies in the market compete on the basis of product quality offered. Major players in this market focus on expanding their manufacturing facilities, R&D investments, infrastructural development, and leverage integration opportunities across the value chain. With these strategies bioprocess chromatography media companies cater increasing demand, ensure competitive effectiveness, develop innovative products & technologies, reduce production costs, and expand their customer base. Some of the bioprocess chromatography media companies profiled in this report include-
• Cytiva
• Thermo Fisher Scientific
• Merck Millipore
• Sunresin New Materials
• Mitsubishi Chemical
• Purolite
• Tosoh
• Sartorius
• JSR Life Sciences
• Repligen

Bioprocess Chromatography Media Market by Segment

The study includes a forecast for the global bioprocess chromatography media market by type, application, and region.

Bioprocess Chromatography Media Market by Type [Value from 2019 to 2031]:


• Gel Filtration
• Ion Exchange
• Hydrophobic
• Affinity
• Others

Bioprocess Chromatography Media Market by Application [Value from 2019 to 2031]:


• Biopharmaceuticals
• Laboratory Research
• Others

Bioprocess Chromatography Media Market by Region [Value from 2019 to 2031]:


• North America
• Europe
• Asia Pacific
• The Rest of the World

Country Wise Outlook for the Bioprocess Chromatography Media Market

The bioprocess chromatography media industry is experiencing tremendous transformation, fueled by the growing need for sophisticated purification technologies in the biopharmaceuticals sector. With the increasing pipeline of biologics, such as monoclonal antibodies, vaccines, and cell and gene therapies, worldwide, cost- and efficient-separation technologies assume precedence. Recent innovations center on improved media performance, maximizing throughput, and guaranteeing consistent product quality, aligning with industry movement towards more intensified and continuous bioprocessing approaches.
• United States: In the United States, current trends in the bioprocess chromatography media market are driven significantly by the strong growth of its biopharmaceutical industry, especially in monoclonal antibodies and gene therapies. There is a particular emphasis on creating new, high-capacity, and high-resolution media capable of supporting complex biomolecules. US companies are investing in single-use and automation technologies to drive purification process streamlining to lower manufacturing costs and advance drug development timelines to respond to the growing demand for sophisticated therapeutics.
• China: China bioprocess chromatography media market is witnessing aggressive developments driven by strong government support for its growing biopharmaceutical industry and domestic substitution drive. Notable recent developments include huge investments in indigenous research and development infrastructures, resulting in the growth of local media manufacturers providing competitive products. The attention is on creating cost-effective, high-performance media applicable for large-scale bioproduction, which mirrors China aspiration to be a key participant in global biomanufacturing.
• Germany: Germany, with its vigorous focus on cutting-edge biotechnology and pharmaceutical production, is experiencing trends in the market for bioprocess chromatography media based on innovation and efficiency. German firms are leading the way to create new media chemistries as well as optimize current ones for better selectivity, binding capacity, and scalability. Continuous bioprocessing and integrated downstream purification platforms are the main thrusts, using high-performance media to increase productivity and eliminate processing bottlenecks for biologics manufacturing.
• India: India bioprocess chromatography media market is on the rise, fueled by its status as a center for global generic drug manufacturing and a fast-growing biosimilar sector. Latest trends involve surging investment in biopharmaceutical production facilities and an escalating requirement for affordable purification solutions. Indian businesses are looking to implement advanced chromatography media and technologies for verifying the quality and purity of their biosimilars and biologics in accordance with global regulatory standards and to meet both domestic and export markets.
• Japan: In Japan, the recent trends in the market for bioprocess chromatography media are dominated by emphasis on high quality, efficiency, and technological accuracy. Japanese biopharmaceuticals are embracing sophisticated chromatography media for purification of extremely sensitive biologics and new therapies. Developing media that provide superior resolution and reproducibility is stressed, which is essential to satisfy rigorous quality demands and facilitate production of innovative biopharmaceuticals for a demanding market.
Lucintel Analytics Dashboard

Features of the Global Bioprocess Chromatography Media Market

Market Size Estimates: Bioprocess chromatography media market size estimation in terms of value ($B).
Trend and Forecast Analysis: Market trends (2019 to 2024) and forecast (2025 to 2031) by various segments and regions.
Segmentation Analysis: Bioprocess chromatography media market size by type, application, and region in terms of value ($B).
Regional Analysis: Bioprocess chromatography media market breakdown by North America, Europe, Asia Pacific, and Rest of the World.
Growth Opportunities: Analysis of growth opportunities in different type, application, and regions for the bioprocess chromatography media market.
Strategic Analysis: This includes M&A, new product development, and competitive landscape of the bioprocess chromatography media market.
Analysis of competitive intensity of the industry based on Porter’s Five Forces model.

Lucintel Consulting Services

FAQ

Q1. What is the growth forecast for bioprocess chromatography media market?
Answer: The global bioprocess chromatography media market is expected to grow with a CAGR of 5.1% from 2025 to 2031.
Q2. What are the major drivers influencing the growth of the bioprocess chromatography media market?
Answer: The major drivers for this market are the rising demand for biologics & biosimilars, the growing focus on personalized medicine, and the increasing adoption of advanced bioprocessing technologies.
Q3. What are the major segments for bioprocess chromatography media market?
Answer: The future of the bioprocess chromatography media market looks promising with opportunities in the biopharmaceutical and laboratory research markets.
Q4. Who are the key bioprocess chromatography media market companies?
Answer: Some of the key bioprocess chromatography media companies are as follows:
• Cytiva
• Thermo Fisher Scientific
• Merck Millipore
• Sunresin New Materials
• Mitsubishi Chemical
• Purolite
• Tosoh
• Sartorius
• JSR Life Sciences
• Repligen
Q5. Which bioprocess chromatography media market segment will be the largest in future?
Answer: Lucintel forecasts that, within the type category, ion exchange is expected to witness the highest growth over the forecast period.
Q6. In bioprocess chromatography media market, which region is expected to be the largest in next 5 years?
Answer: In terms of region, North America is expected to witness the highest growth over the forecast period.
Q7. Do we receive customization in this report?
Answer: Yes, Lucintel provides 10% customization without any additional cost.

This report answers following 11 key questions:

Q.1. What are some of the most promising, high-growth opportunities for the bioprocess chromatography media market by type (gel filtration, ion exchange, hydrophobic, affinity, and others), application (biopharmaceuticals, laboratory research, and others), and region (North America, Europe, Asia Pacific, and the Rest of the World)?
Q.2. Which segments will grow at a faster pace and why?
Q.3. Which region will grow at a faster pace and why?
Q.4. What are the key factors affecting market dynamics? What are the key challenges and business risks in this market?
Q.5. What are the business risks and competitive threats in this market?
Q.6. What are the emerging trends in this market and the reasons behind them?
Q.7. What are some of the changing demands of customers in the market?
Q.8. What are the new developments in the market? Which companies are leading these developments?
Q.9. Who are the major players in this market? What strategic initiatives are key players pursuing for business growth?
Q.10. What are some of the competing products in this market and how big of a threat do they pose for loss of market share by material or product substitution?
Q.11. What M&A activity has occurred in the last 5 years and what has its impact been on the industry?

For any questions related to Bioprocess Chromatography Media Market, Bioprocess Chromatography Media Market Size, Bioprocess Chromatography Media Market Growth, Bioprocess Chromatography Media Market Analysis, Bioprocess Chromatography Media Market Report, Bioprocess Chromatography Media Market Share, Bioprocess Chromatography Media Market Trends, Bioprocess Chromatography Media Market Forecast, Bioprocess Chromatography Media Companies, write Lucintel analyst at email: helpdesk@lucintel.com. We will be glad to get back to you soon.
                                                            Table of Contents

            1. Executive Summary

            2. Global Bioprocess Chromatography Media Market : Market Dynamics
                        2.1: Introduction, Background, and Classifications
                        2.2: Supply Chain
                        2.3: Industry Drivers and Challenges

            3. Market Trends and Forecast Analysis from 2019 to 2031
                        3.1. Macroeconomic Trends (2019-2024) and Forecast (2025-2031)
                        3.2. Global Bioprocess Chromatography Media Market Trends (2019-2024) and Forecast (2025-2031)
                        3.3: Global Bioprocess Chromatography Media Market by Type
                                    3.3.1: Gel Filtration
                                    3.3.2: Ion Exchange
                                    3.3.3: Hydrophobic
                                    3.3.4: Affinity
                                    3.3.5: Others
                        3.4: Global Bioprocess Chromatography Media Market by Application
                                    3.4.1: Biopharmaceuticals
                                    3.4.2: Laboratory Research
                                    3.4.3: Others

            4. Market Trends and Forecast Analysis by Region from 2019 to 2031
                        4.1: Global Bioprocess Chromatography Media Market by Region
                        4.2: North American Bioprocess Chromatography Media Market
                                    4.2.1: North American Market by Type: Gel Filtration, Ion Exchange, Hydrophobic, Affinity, and Others
                                    4.2.2: North American Market by Application: Biopharmaceuticals, Laboratory Research, and Others
                        4.3: European Bioprocess Chromatography Media Market
                                    4.3.1: European Market by Type: Gel Filtration, Ion Exchange, Hydrophobic, Affinity, and Others
                                    4.3.2: European Market by Application: Biopharmaceuticals, Laboratory Research, and Others
                        4.4: APAC Bioprocess Chromatography Media Market
                                    4.4.1: APAC Market by Type: Gel Filtration, Ion Exchange, Hydrophobic, Affinity, and Others
                                    4.4.2: APAC Market by Application: Biopharmaceuticals, Laboratory Research, and Others
                        4.5: ROW Bioprocess Chromatography Media Market
                                    4.5.1: ROW Market by Type: Gel Filtration, Ion Exchange, Hydrophobic, Affinity, and Others
                                    4.5.2: ROW Market by Application: Biopharmaceuticals, Laboratory Research, and Others

            5. Competitor Analysis
                        5.1: Product Portfolio Analysis
                        5.2: Operational Integration
                        5.3: Porter’s Five Forces Analysis

            6. Growth Opportunities and Strategic Analysis
                        6.1: Growth Opportunity Analysis
                                    6.1.1: Growth Opportunities for the Global Bioprocess Chromatography Media Market by Type
                                    6.1.2: Growth Opportunities for the Global Bioprocess Chromatography Media Market by Application
                                    6.1.3: Growth Opportunities for the Global Bioprocess Chromatography Media Market by Region
                        6.2: Emerging Trends in the Global Bioprocess Chromatography Media Market
                        6.3: Strategic Analysis
                                    6.3.1: New Product Development
                                    6.3.2: Capacity Expansion of the Global Bioprocess Chromatography Media Market
                                    6.3.3: Mergers, Acquisitions, and Joint Ventures in the Global Bioprocess Chromatography Media Market
                                    6.3.4: Certification and Licensing

            7. Company Profiles of Leading Players
                        7.1: Cytiva
                        7.2: Thermo Fisher Scientific
                        7.3: Merck Millipore
                        7.4: Sunresin New Materials
                        7.5: Mitsubishi Chemical
                        7.6: Purolite
                        7.7: Tosoh
                        7.8: Sartorius
                        7.9: JSR Life Sciences
                        7.10: Repligen
.

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Lucintel has been in the business of market research and management consulting since 2000 and has published over 1000 market intelligence reports in various markets / applications and served over 1,000 clients worldwide. This study is a culmination of four months of full-time effort performed by Lucintel's analyst team. The analysts used the following sources for the creation and completion of this valuable report:
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